Monday, August 24, 2015

The human oral metaproteome


Please, fly into our open maw, and have at it.
 Image source: http://coglab.hbcse.tifr.res.in/teacher-resources/multimedia-resources/symbiosis/photographs/crocodileplover.jpg
In a recent article in Proteomics, scientists have identified a catalog of proteins from the human oral biofilm. They identified about 8000 bacterial proteins in 17 individuals and found out that 4 bacterial genera constitute 60-90% of the bacterial diversity. They also identified several proteins that could serve as potential biomarkers for dental caries. The methodology consisted of Hydrophilic interaction liquid chromatography (HILIC) and LTQ-Orbitrap Velos (Thermo Fisher Scientific, Germany) and XL (Thermo Fisher Scientific, Germany) instruments.

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