Showing posts with label oral. Show all posts
Showing posts with label oral. Show all posts

Monday, August 24, 2015

The human oral metaproteome


Please, fly into our open maw, and have at it.
 Image source: http://coglab.hbcse.tifr.res.in/teacher-resources/multimedia-resources/symbiosis/photographs/crocodileplover.jpg
In a recent article in Proteomics, scientists have identified a catalog of proteins from the human oral biofilm. They identified about 8000 bacterial proteins in 17 individuals and found out that 4 bacterial genera constitute 60-90% of the bacterial diversity. They also identified several proteins that could serve as potential biomarkers for dental caries. The methodology consisted of Hydrophilic interaction liquid chromatography (HILIC) and LTQ-Orbitrap Velos (Thermo Fisher Scientific, Germany) and XL (Thermo Fisher Scientific, Germany) instruments.