Proteomics is a field in science devoted to large-scale structural and functional characterization of proteins. Why is it important? Studying DNA and mRNA can give you only so much information. Studying proteins is the next step because proteins are the actual chemical messengers in a biological system.
Proteomics is much more complicated. As the article in Wikipedia says:
"After genomics and transcriptomics, proteomics is the next step in the study of biological systems. It is more complicated than genomics because an organism's genome is more or less constant, whereas the proteome differs from cell to cell and from time to time. Distinct genes are expressed in different cell types, which means that even the basic set of proteins that are produced in a cell needs to be identified.
In the past this phenomenon was done by mRNA analysis, but it was found not to correlate with protein content.It is now known that mRNA is not always translated into protein, and the amount of protein produced for a given amount of mRNA depends on the gene it is transcribed from and on the current physiological state of the cell. Proteomics confirms the presence of the protein and provides a direct measure of the quantity present."
Source: http://en.wikipedia.org/wiki/Proteomics
So why this blog? Proteomics is becoming popular day by day. Starting off with proteomics research is difficult because you need an in-house expert or depend on external help. Resources are scattered around the net and this blog aims to make an index of resources on proteomics and it's work-horse- mass spectrometry.
Proteomics is much more complicated. As the article in Wikipedia says:
"After genomics and transcriptomics, proteomics is the next step in the study of biological systems. It is more complicated than genomics because an organism's genome is more or less constant, whereas the proteome differs from cell to cell and from time to time. Distinct genes are expressed in different cell types, which means that even the basic set of proteins that are produced in a cell needs to be identified.
In the past this phenomenon was done by mRNA analysis, but it was found not to correlate with protein content.It is now known that mRNA is not always translated into protein, and the amount of protein produced for a given amount of mRNA depends on the gene it is transcribed from and on the current physiological state of the cell. Proteomics confirms the presence of the protein and provides a direct measure of the quantity present."
Source: http://en.wikipedia.org/wiki/Proteomics
So why this blog? Proteomics is becoming popular day by day. Starting off with proteomics research is difficult because you need an in-house expert or depend on external help. Resources are scattered around the net and this blog aims to make an index of resources on proteomics and it's work-horse- mass spectrometry.
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